T11I (p.Thr11Ile) variant of POR (NADPH--cytochrome P450 reductase)
T11I (p.Thr11Ile) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
T11I (p.Thr11Ile) variant details
- p.Thr11Ile
- gnomAD 7-75954024-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.10
- CADD 11.30
- PolyPhen-2 0.03
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available