S4S (p.Ser4Ser) variant of POR (NADPH--cytochrome P450 reductase)
S4S (p.Ser4Ser) in POR (NADPH--cytochrome P450 reductase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
S4S (p.Ser4Ser) variant details
- p.Ser4Ser
- rs11979171
- gnomAD 7-75968099-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.108
- CADD 3.82
- Most common in the HGDP:TU population (allele frequency 0.05)
- Structural context available
- Literature evidence available