S24G (p.Ser24Gly) variant of POR (NADPH--cytochrome P450 reductase)
S24G (p.Ser24Gly) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S24G (p.Ser24Gly) variant details
- p.Ser24Gly
- gnomAD 7-75954071-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.11
- CADD 17.50
- PolyPhen-2 0.01
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available