R45Q (p.Arg45Gln) variant of POR (NADPH--cytochrome P450 reductase)
R45Q (p.Arg45Gln) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
R45Q (p.Arg45Gln) variant details
- p.Arg45Gln
- rs1025967984
- gnomAD 7-75968255-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0804
- CADD 0.03
- Most common in the East Asian population (allele frequency 0.00011)
- Structural context available
- Literature evidence available