R45G (p.Arg45Gly) variant of POR (NADPH--cytochrome P450 reductase)
R45G (p.Arg45Gly) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
R45G (p.Arg45Gly) variant details
- p.Arg45Gly
- rs1554555627
- gnomAD 7-75968254-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0786
- CADD 0.08
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available
- Literature evidence available