G2G (p.Gly2Gly) variant of POR (NADPH--cytochrome P450 reductase)
G2G (p.Gly2Gly) in POR (NADPH--cytochrome P450 reductase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G2G (p.Gly2Gly) variant details
- p.Gly2Gly
- rs10262966
- gnomAD 7-75954007-A-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.234
- CADD 9.66
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Cited in: Pharmacogenomics of human P450 oxidoreductase. (PMID 24847272)
- Cited in: Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and… (PMID 21514219)