F23L (p.Phe23Leu) variant of POR (NADPH--cytochrome P450 reductase)
F23L (p.Phe23Leu) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
F23L (p.Phe23Leu) variant details
- p.Phe23Leu
- gnomAD 7-75954068-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.21
- CADD 15.80
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available