V97M (p.Val97Met) variant of PON1 (Serum paraoxonase/arylesterase 1)
V97M (p.Val97Met) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
V97M (p.Val97Met) variant details
- p.Val97Met
- ExAC rs753660246
- TOPMed rs753660246
- gnomAD rs753660246
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.17
- CADD 23.80
- PolyPhen-2 0.81
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available