V131M (p.Val131Met) variant of PON1 (Serum paraoxonase/arylesterase 1)
V131M (p.Val131Met) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
V131M (p.Val131Met) variant details
- p.Val131Met
- TOPMed rs934788389
- gnomAD rs934788389
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.46
- CADD 24.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available