V109I (p.Val109Ile) variant of PON1 (Serum paraoxonase/arylesterase 1)
V109I (p.Val109Ile) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
V109I (p.Val109Ile) variant details
- p.Val109Ile
- 1000Genomes rs61736513
- ESP rs61736513
- ExAC rs61736513
- TOPMed rs61736513
- Missense
- Variant Prioritization Score for Impact Estimate 0.0481
- REVEL 0.01
- CADD 5.92
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the HGDP:YORUBA population (allele frequency 0.024)
- Structural context available