T119R (p.Thr119Arg) variant of PON1 (Serum paraoxonase/arylesterase 1)
T119R (p.Thr119Arg) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
T119R (p.Thr119Arg) variant details
- p.Thr119Arg
- TOPMed rs1298308000
- gnomAD rs1298308000
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.28
- CADD 26.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available