S81R (p.Ser81Arg) variant of PON1 (Serum paraoxonase/arylesterase 1)
S81R (p.Ser81Arg) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data and structural context.
S81R (p.Ser81Arg) variant details
- p.Ser81Arg
- gnomAD rs1295722236
- Missense
- Variant Prioritization Score for Impact Estimate 0.0296
- REVEL 0.02
- CADD 0.11
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available