S66N (p.Ser66Asn) variant of PON1 (Serum paraoxonase/arylesterase 1)
S66N (p.Ser66Asn) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
S66N (p.Ser66Asn) variant details
- p.Ser66Asn
- Ensembl rs1807776938
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.29
- CADD 25.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available