S23A (p.Ser23Ala) variant of PON1 (Serum paraoxonase/arylesterase 1)
S23A (p.Ser23Ala) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S23A (p.Ser23Ala) variant details
- p.Ser23Ala
- ESP rs146211440
- ExAC rs146211440
- TOPMed rs146211440
- gnomAD rs146211440
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.09
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available