S110P (p.Ser110Pro) variant of PON1 (Serum paraoxonase/arylesterase 1)
S110P (p.Ser110Pro) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S110P (p.Ser110Pro) variant details
- p.Ser110Pro
- ExAC rs773545753
- TOPMed rs773545753
- gnomAD rs773545753
- Missense
- Variant Prioritization Score for Impact Estimate 0.0998
- REVEL 0.09
- CADD 7.83
- PolyPhen-2 0.04
- SIFT 0.20
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available