N60K (p.Asn60Lys) variant of PON1 (Serum paraoxonase/arylesterase 1)
N60K (p.Asn60Lys) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
N60K (p.Asn60Lys) variant details
- p.Asn60Lys
- TOPMed rs35431117
- gnomAD rs35431117
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.11
- CADD 20.70
- PolyPhen-2 0.29
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available