M88T (p.Met88Thr) variant of PON1 (Serum paraoxonase/arylesterase 1)
M88T (p.Met88Thr) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
M88T (p.Met88Thr) variant details
- p.Met88Thr
- ESP rs367566813
- ExAC rs367566813
- TOPMed rs367566813
- gnomAD rs367566813
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.27
- CADD 24.50
- PolyPhen-2 0.67
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 6.6e-05)
- Structural context available