L90P (p.Leu90Pro) variant of PON1 (Serum paraoxonase/arylesterase 1)
L90P (p.Leu90Pro) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L90P (p.Leu90Pro) variant details
- p.Leu90Pro
- 1000Genomes rs72552788
- ESP rs72552788
- ExAC rs72552788
- TOPMed rs72552788
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- REVEL 0.64
- CADD 29.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the 1KG:IBS population (allele frequency 0.0048)
- Structural context available