K70Q (p.Lys70Gln) variant of PON1 (Serum paraoxonase/arylesterase 1)
K70Q (p.Lys70Gln) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K70Q (p.Lys70Gln) variant details
- p.Lys70Gln
- ExAC rs745352941
- TOPMed rs745352941
- gnomAD rs745352941
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.17
- CADD 19.80
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available