G83R (p.Gly83Arg) variant of PON1 (Serum paraoxonase/arylesterase 1)
G83R (p.Gly83Arg) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
G83R (p.Gly83Arg) variant details
- p.Gly83Arg
- ExAC rs755298318
- gnomAD rs755298318
- Missense
- Variant Prioritization Score for Impact Estimate 0.71
- REVEL 0.64
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available