G11R (p.Gly11Arg) variant of PON1 (Serum paraoxonase/arylesterase 1)
G11R (p.Gly11Arg) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G11R (p.Gly11Arg) variant details
- p.Gly11Arg
- Ensembl rs2116333838
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.25
- CADD 23.60
- PolyPhen-2 0.83
- SIFT 0.03
- Most common in the HGDP:MANDENKA population (allele frequency 0.025)
- Structural context available