G104R (p.Gly104Arg) variant of PON1 (Serum paraoxonase/arylesterase 1)
G104R (p.Gly104Arg) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G104R (p.Gly104Arg) variant details
- p.Gly104Arg
- TOPMed rs1205741356
- gnomAD rs1205741356
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.07
- CADD 21.80
- PolyPhen-2 0.03
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available