F120C (p.Phe120Cys) variant of PON1 (Serum paraoxonase/arylesterase 1)
F120C (p.Phe120Cys) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
F120C (p.Phe120Cys) variant details
- p.Phe120Cys
- ExAC rs368620674
- gnomAD rs368620674
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.28
- CADD 27.60
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available