E150K (p.Glu150Lys) variant of PON1 (Serum paraoxonase/arylesterase 1)
E150K (p.Glu150Lys) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
E150K (p.Glu150Lys) variant details
- p.Glu150Lys
- ExAC rs746170718
- gnomAD rs746170718
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.10
- CADD 24.30
- PolyPhen-2 0.14
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available