D89Y (p.Asp89Tyr) variant of PON1 (Serum paraoxonase/arylesterase 1)
D89Y (p.Asp89Tyr) in PON1 (Serum paraoxonase/arylesterase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
D89Y (p.Asp89Tyr) variant details
- p.Asp89Tyr
- TOPMed rs1807745574
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.41
- CADD 24.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available