R19S (p.Arg19Ser) variant of POLD1 (P28340)
R19S (p.Arg19Ser) in POLD1 (P28340) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
R19S (p.Arg19Ser) variant details
- p.Arg19Ser
- cosmic curated COSV10148
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.04
- CADD 18.80
- PolyPhen-2 0.02
- SIFT 0.05
- Population evidence available
- Structural context available