L22L (p.Leu22Leu) variant of POLD1 (P28340)
L22L (p.Leu22Leu) in POLD1 (P28340) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L22L (p.Leu22Leu) variant details
- p.Leu22Leu
- rs745941251
- gnomAD 19-50398917-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.142
- CADD 1.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available