G3V (p.Gly3Val) variant of POLD1 (P28340)
G3V (p.Gly3Val) in POLD1 (P28340) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G3V (p.Gly3Val) variant details
- p.Gly3Val
- NCI-TCGA Cosmic COSV1014
- cosmic curated COSV10148
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.05
- CADD 22.80
- PolyPhen-2 0.02
- SIFT 0.12
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available