G10E (p.Gly10Glu) variant of POLD1 (P28340)
G10E (p.Gly10Glu) in POLD1 (P28340) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G10E (p.Gly10Glu) variant details
- p.Gly10Glu
- cosmic curated COSV10611
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.06
- CADD 18.70
- PolyPhen-2 0.03
- SIFT 0.11
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available