D37V (p.Asp37Val) variant of POLD1 (P28340)
D37V (p.Asp37Val) in POLD1 (P28340) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D37V (p.Asp37Val) variant details
- p.Asp37Val
- gnomAD rs1486924942
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.05
- CADD 23.80
- PolyPhen-2 0.02
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available