D27Y (p.Asp27Tyr) variant of POLD1 (P28340)
D27Y (p.Asp27Tyr) in POLD1 (P28340) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
D27Y (p.Asp27Tyr) variant details
- p.Asp27Tyr
- gnomAD 19-50398930-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.09
- CADD 20.30
- PolyPhen-2 0.23
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available