D25Y (p.Asp25Tyr) variant of POLD1 (P28340)
D25Y (p.Asp25Tyr) in POLD1 (P28340) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
D25Y (p.Asp25Tyr) variant details
- p.Asp25Tyr
- gnomAD 19-50398924-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.08
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available