C42R (p.Cys42Arg) variant of PMP22 (Peripheral myelin protein 22)

C42R (p.Cys42Arg) in PMP22 (Peripheral myelin protein 22) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Charcot-Marie-Tooth disease, type I; Charcot-Marie-Tooth disease, type IA; not p. The record also includes published literature and structural context.

C42R (p.Cys42Arg) variant details