L86M (p.Leu86Met) variant of PLP1 (Myelin proteolipid protein)
L86M (p.Leu86Met) in PLP1 (Myelin proteolipid protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L86M (p.Leu86Met) variant details
- p.Leu86Met
- gnomAD rs1416305526
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available