L85L (p.Leu85Leu) variant of PLP1 (Myelin proteolipid protein)
L85L (p.Leu85Leu) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
L85L (p.Leu85Leu) variant details
- p.Leu85Leu
- rs140047941
- gnomAD X-103786528-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.58
- CADD 9.76
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available
- Literature evidence available