L81L (p.Leu81Leu) variant of PLP1 (Myelin proteolipid protein)
L81L (p.Leu81Leu) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L81L (p.Leu81Leu) variant details
- p.Leu81Leu
- gnomAD X-103786516-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.375
- CADD 11.50
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available