L46L (p.Leu46Leu) variant of PLP1 (Myelin proteolipid protein)
L46L (p.Leu46Leu) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
L46L (p.Leu46Leu) variant details
- p.Leu46Leu
- rs771833180
- gnomAD X-103785715-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.536
- CADD 8.23
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available