I62T (p.Ile62Thr) variant of PLP1 (Myelin proteolipid protein)
I62T (p.Ile62Thr) in PLP1 (Myelin proteolipid protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
I62T (p.Ile62Thr) variant details
- p.Ile62Thr
- gnomAD X-103785762-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- CADD 18.20
- PolyPhen-2 0.14
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available
- Literature evidence available