G42G (p.Gly42Gly) variant of PLP1 (Myelin proteolipid protein)
G42G (p.Gly42Gly) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G42G (p.Gly42Gly) variant details
- p.Gly42Gly
- rs896775245
- gnomAD X-103785703-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.137
- CADD 8.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available