G13R (p.Gly13Arg) variant of PLP1 (Myelin proteolipid protein)
G13R (p.Gly13Arg) in PLP1 (Myelin proteolipid protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
G13R (p.Gly13Arg) variant details
- p.Gly13Arg
- ExAC rs755645540
- gnomAD rs755645540
- Missense
- Variant Prioritization Score for Impact Estimate 0.72
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available