F80S (p.Phe80Ser) variant of PLP1 (Myelin proteolipid protein)
F80S (p.Phe80Ser) in PLP1 (Myelin proteolipid protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
F80S (p.Phe80Ser) variant details
- p.Phe80Ser
- TOPMed rs2074498051
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- CADD 28.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available