E5E (p.Glu5Glu) variant of PLP1 (Myelin proteolipid protein)
E5E (p.Glu5Glu) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
E5E (p.Glu5Glu) variant details
- p.Glu5Glu
- rs753140839
- gnomAD X-103785592-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.321
- CADD 9.01
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available