C33C (p.Cys33Cys) variant of PLP1 (Myelin proteolipid protein)
C33C (p.Cys33Cys) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
C33C (p.Cys33Cys) variant details
- p.Cys33Cys
- rs2074489420
- gnomAD X-103785676-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.469
- CADD 13.30
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available