A21A (p.Ala21Ala) variant of PLP1 (Myelin proteolipid protein)
A21A (p.Ala21Ala) in PLP1 (Myelin proteolipid protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
A21A (p.Ala21Ala) variant details
- p.Ala21Ala
- rs753285570
- gnomAD X-103785640-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.594
- CADD 12.80
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available