p.Ala58 Asp59insArgGlyLeuLeuTer variant of PLCG2 (P16885)

Name: PLCG2 p.Ala58 Asp59insArgGlyLeuLeuTer variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

p.Ala58 Asp59insArgGlyLeuLeuTer in PLCG2 (P16885) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.

p.Ala58 Asp59insArgGlyLeuLeuTer variant details

gnomAD 16-81786163-T-TCG
Stop Gained
Variant Prioritization Score for Impact Estimate 0.321
CADD 34.00
Most common in the Non-Finnish European population (allele frequency 3.6e-06)
Structural context available
Literature evidence available