V45V (p.Val45Val) variant of PLCG2 (P16885)
V45V (p.Val45Val) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V45V (p.Val45Val) variant details
- p.Val45Val
- gnomAD 16-81786124-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.392
- CADD 10.80
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.732
- Literature evidence available