V27V (p.Val27Val) variant of PLCG2 (P16885)
V27V (p.Val27Val) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V27V (p.Val27Val) variant details
- p.Val27Val
- rs1311473662
- gnomAD 16-81786070-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.653
- CADD 8.96
- Population evidence available
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.956
- Literature evidence available