T57N (p.Thr57Asn) variant of PLCG2 (P16885)
T57N (p.Thr57Asn) in PLCG2 (P16885) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
T57N (p.Thr57Asn) variant details
- p.Thr57Asn
- gnomAD rs1429527089
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- CADD 23.70
- PolyPhen-2 0.96
- SIFT 0.26
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available