T42T (p.Thr42Thr) variant of PLCG2 (P16885)
T42T (p.Thr42Thr) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T42T (p.Thr42Thr) variant details
- p.Thr42Thr
- rs753972799
- gnomAD 16-81786115-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0886
- CADD 1.12
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.385
- Literature evidence available