T3T (p.Thr3Thr) variant of PLCG2 (P16885)
T3T (p.Thr3Thr) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T3T (p.Thr3Thr) variant details
- p.Thr3Thr
- rs769990892
- gnomAD 16-81785998-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.501
- CADD 6.75
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.0169
- Literature evidence available